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Depth Filter Modules for Biopharmaceutical Applications

DEPTH-CLEAR P Series depth filter modules are specifically formulated to meet the performance demands of biopharmaceutical and biotech applications. The filter media utilize mechanical and electrokinetic adsorptive capture mechanisms to remove particles, microorganisms, colloids, and pyrogen from critical process streams. Purolator, a leader in depth media development, has invested years of research and development to create a range of filter grades to meet stringent application requirements.

The DEPTH-CLEAR proprietary formulation process produces filter media with exceptionally high, effective filtration area that provides superior particle retention, high contaminant holding capacity, and long on-stream filter life. Manufacturing by means of an advanced, highly automated production process results in very consistent product quality and filtration performance. Purolator can provide technical assistance to validate the performance of DEPTH-CLEAR filters in new processes and applications.

DEPTH-CLEAR Pharmaceutical Grade (P Series) filter modules are manufactured to procedures described in a Drug Master File (DMF) on record at the National Center for Drugs and Biologics. The filter media is non-toxic in accordance with systemic injection testing. A special low extractable (LE Series) grade is available for susceptible processes and high purity applications. The DEPTH-CLEAR P & LE grades have complete product control and traceability, as set forth in the Drug Master File.
Unit of Measure

Specifications

Media Type

 N/A Non-Asbestos

Grade Designation

 N/A 150

Formulation

 N/A K Grade

Series

 N/A Pharmaceutical

Type

 N/A No Handles

Number of Cells

 N/A 14

Performance Specifications

Differential Pressure @ 140ºF (60ºC)

 N/A to 35 psid2.5 bar

Maximum Operating Temperature

 N/A 185 ºF85 ºC

Recommended Flow Rate

 N/A 0.5 to 1.0 gpm/ft²20 to 40 lpm/m²

FDA Conformity

 N/A All materials conform to FDA standards regarding material contact during food and beverage processing.

Toxicity

 N/A DEPTH-CLEAR Series filter components comply with USP XXIII standards for Class VI-121 plastics.

Materials of Construction

Media Material

 N/A Cellulose Fibers with Inorganic Filter Aids

End Caps Material

 N/A Polypropylene

Cartridge Straps Material

 N/A Stainless Steel

Gasket Material

 N/A Ethylene Propylene Neoprene Nitrile PTFE Silicone Viton®

Nominal Dimensions

Diameter

 N/A 16 3/4 in42.5 cm

Height

 N/A 10 7/8 in27.6 cm

Filter Area

 N/A 38 ft²3.5 m²

Benefits

N/A

  • High surface area filter modules provide superior filtration performance and long on-stream life cycles.
  • Proprietary formulation process results in depth media with exceptional particle retention via mechanical and electrokinetic capture.
  • The advanced manufacturing process control results in very uniform filtration media and consistent lot-to-lot performance.
  • Non toxic - Meets the requirements of USP XXIII Class VI Biological Tests for Plastics.
  • Special low extractable formulation (LE Series) available for sensitive applications.
  • Special formulations available for high temperature applications (>140ºF).
  • Filter modules available in a wide variety of dimensions and configurations to fit most standard housings.

Applications

N/A

  • Antibiotics
  • Blood Products
  • Intravenous Solutions
  • Cell Separation
  • Cough Syrups
  • Chromatography Column Protection
  • Post Fermentation Clarification
  • Small and Large Volume Parentals

Note

N/A Viton and PTFE are registered trademarks of E.I. duPont de Nemours and Company.
Depth-Clear and The Clear Advantage are trademarks of Clarcor, Inc.